Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
A. E. P. Loftus, M. S. Romano, A. Nguyen Phuong, M. T. Muir, J. C. Dawson, L. Avalle, A. T. Douglas, R. L. Mort, A. Byron, N. O. Carragher, S. M. Pollard, V. G. Brunton, M. C. Frame
This study identifies a novel ILK-STAT3 pathway that regulates phenotypic plasticity and mesenchymal state in mouse glioblastoma stem cells.
bioRxiv · Jul 19, 2023 · PreprintCancer Biology
H. F. Titmarsh, A. von Kriegsheim, J. C. Wills, R. A. O'Connor, K. Dhaliwal, M. C. Frame, S. B. Pattle, D. A. Dorward, A. Byron, A. R. Akram
The paper identifies tumour-specific ECM proteome signatures in NSCLC patients using mass spectrometry, finding 161 differentially regulated matrisome proteins and two novel extracellular markers associated with poorer survival.
bioRxiv · Sep 29, 2022 · PreprintCancer Biology
L. de Koning, S. Bernhardt, K. G. Macleod, B. Ouine, A. Cartier, V. Sibut, N. O. Carragher, U. Korf, B. Serrels, A. Byron
This paper integrates multicenter reverse-phase protein array data from breast cancer cell responses to two drugs, quantifying 86,832 spots across three platforms to create a public resource for comparing RPPA workflows.
bioRxiv · Aug 31, 2021 · PreprintBiochemistry
A. Byron, B. G. C. Griffith, A. Herrero, A. E. P. Loftus, E. S. Koeleman, J. C. Dawson, L. Kogerman, N. McGivern, J. Culley, G. R. Grimes, B. Serrels, A. von Kriegsheim, V. G. Brunton, M. C. Frame
The paper identifies a nucleo-adhesome, showing that adhesion proteins localize to the nucleus and regulate transcription through interactions like FAK and Hic-5.
bioRxiv · Aug 31, 2021Cell Biology
F. Li Mow Chee, B. Beernaert, A. E. P. Loftus, Y. Kumar, B. G. C. Griffith, J. C. Wills, A. P. Wheeler, J. D. Armstrong, M. Parsons, I. M. Leigh, C. M. Proby, A. von Kriegsheim, W. A. Bickmore, M. C. Frame, A. Byron
This study identifies Mena's role in regulating the LINC complex and nuclear architecture, linking it to cancer gene expression through nuclear membrane signaling.
bioRxiv · Aug 31, 2021 · PreprintCell Biology
Y. Rabanal-Ruiz, A. Byron, A. Wirth, R. R. Madsen, L. Sedlackova, G. Hewitt, G. Nelson, J. Stingele, R. Faessler, B. Vanhaesebroeck, O. Maddocks, E. Ponimaskin, B. Carroll, V. I. Korolchuk
This study shows that mTORC1 activation by growth factors and amino acids requires its spatial association with focal adhesions, independent of lysosomal distribution.
bioRxiv · Nov 20, 2020Cell Biology
C. Schoenherr, A. Byron, M. C. Frame
This study identifies a novel nuclear scaffolding function of Ambra1 that regulates transcriptional signaling by recruiting chromatin modifiers and transcription factors to control gene expression.
bioRxiv · Jan 8, 2020Cell Biology
A. Byron, S. Bernhardt, B. Ouine, A. Cartier, K. G. Macleod, N. O. Carragher, V. Sibut, U. Korf, B. Serrels, L. de Koning
The paper assesses variability between RPPA platforms and identifies consistent protein expression and phosphorylation signatures across different platforms and workflows.
bioRxiv · Sep 16, 2019Cancer Biology
J. C. Dawson, B. Serrels, A. Byron, M. Muir, A. Makda, A. Garcia-Munoz, A. von Kriegsheim, N. O. Carragher, M. C. Frame
The paper identifies a synergistic combination of FAK and HDAC inhibitors using a chemical-genetic high-content screen, showing efficacy in cancer cell lines and in vivo.
bioRxiv · Mar 27, 2019Cancer Biology