Interleukin-1 regulates follicular T cells during the germinal center reaction
A. Belbezier, P. Engeroff, G. Fourcade, H. Vantomme, R. Vaineau, B. Gouritin, B. Bellier, I. Brocheriou, N. Tchitcheck, S. Graff-Dubois, D. Klatzmann
The paper investigates the role of IL-1 receptors in Tfh and Tfr cells during the germinal center reaction, showing that Tfr cell inhibitory receptors prevent their own activation to allow Tfh cell activation.
bioRxiv · Mar 29, 2023Immunology