Author

B. Boyle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 2 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

E. Normandeau· 2 shared A. M. P. Jones· 1 shared A. Seth· 1 shared B. H. Nelson· 1 shared C. Ctortecka· 1 shared C. Goupil· 1 shared D. R. Mani· 1 shared D. Torkamaneh· 1 shared

Activity by Year

2023-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

E. Normandeau

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Automated single-cell proteomics providing sufficient proteome depth to study complex biology beyond cell type classifications

C. Ctortecka, N. M. Clark, B. Boyle, A. Seth, D. R. Mani, N. Udeshi, S. A. Carr

This study presents an automated single-cell proteomics workflow that identifies over 4,000 proteins per cell and detects key regulatory proteins in LPS-perturbed THP-1 cells.

bioRxiv · Jan 20, 2024 · PreprintBiochemistry

Contrasting levels of transcriptome-wide SNP diversity and decoupled patterns of molecular and functional adaptive variation in conifers

N. Pavy, s. gerardi, J. Prunier, P. Rigault, J. Laroche, G. Daigle, B. Boyle, J. J. MacKay, J. Bousquet

The paper assesses transcriptome-wide SNP diversity and adaptive variation in conifers, finding limited convergence at the molecular level but increased convergence at gene family and biological process levels.

bioRxiv · Dec 12, 2023 · PreprintPlant Biology

Pharmacological control of CAR T cells through CRISPR-driven rapamycin resistance

S. Levesque, G. Carleton, V. Duque, C. Goupil, J.-P. Fiset, S. Villeneuve, E. Normandeau, G. Morin, N. Dumont, B. H. Nelson, J. Laganiere, B. Boyle, J. J. Lum, Y. Doyon

This study develops a CRISPR-based method to create rapamycin-resistant CAR-T cells, enabling pharmacological control of their activity in cancer therapy.

bioRxiv · Sep 14, 2023 · PreprintCancer Biology

Comparative Restriction Enzyme Analysis of Methylation (CREAM) Reveals Methylome Variability Within a Clonal In Vitro Cannabis Population

J. Boissinot, K. Adamek, A. M. P. Jones, E. Normandeau, B. Boyle, D. Torkamaneh

The paper introduces CREAM, a method to assess DNA methylation in cannabis clones, finding preserved methylation patterns across subcultures and identifying epigenetic variability in tissue-cultured cannabis.

bioRxiv · Aug 18, 2023 · PreprintPlant Biology