UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFRsignaling
S. TORRINO, V. TIROILLE, B. DOLFI, M. DUFIES, C. HINAULT, L. BONESSO, S. DAGNINO, J. P. UHLER, M. IRONDELLE, A.-S. GAY, L. FLEURIOT, D. Debayle, S. LACAS-GERVAIS, M. CORMONT, T. BERTERO, , S. CLAVEL
This study shows UBTD1 regulates EGFR signaling by controlling ceramide levels and endolysosomal positioning through ubiquitination of ASAH1 and SQSTM1/p62.
bioRxiv · May 20, 2020Cell Biology