Cell BiologybioRxiv
UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFRsignaling
S. TORRINO, V. TIROILLE, B. DOLFI…·S. CLAVEL
This study shows UBTD1 regulates EGFR signaling by controlling ceramide levels and endolysosomal positioning through ubiquitination of ASAH1 and SQSTM1/p62.
DOI 10.7554/elife.68348