In vitro and in vivo analysis of microvesicle-mediated metastasis using a bright, red-shifted bioluminescent reporter protein of extracellular vesicles
A. A. Zarea, G. I. Perez, D. Broadbent, B. Dolgikh, M. P. Bernard, A. Withrow, A. McGill, V. Toomajian, L. K. Thampy, J. Harkema, J. R. Walker, T. A. Kirkland, M. H. Bachmann, J. Schmidt, M. Kanada
This study uses a bioluminescent reporter to track extracellular vesicles in vivo and shows their role in metastasis by upregulating LC3 in lung tissue.
bioRxiv · Jul 23, 2021Cancer Biology