Author

J. R. Walker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Evolutionary Biology· 1 Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

T. A. Kirkland· 2 shared A. A. Zarea· 1 shared A. D. Klose· 1 shared A. McGill· 1 shared A. O'Connell· 1 shared A. Withrow· 1 shared B. Dolgikh· 1 shared B. R. Huber· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

T. A. Kirkland

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Identification of NanoLuciferase Substrates Transported by Human ABCB1 and ABCG2 and their Zebrafish Homologs at the Blood-Brain Barrier

C. T. Inglut, J. A. Quinlan, R. W. Robey, J. R. Thomas, J. R. Walker, W. Zhou, H.-C. Huang, M. M. Gottesman

The paper identifies NanoLuciferase substrates transported by human and zebrafish ABC transporters at the BBB, aiding in the development of a transgenic zebrafish model to detect BBB disruptors.

bioRxiv · Oct 20, 2023 · PreprintPharmacology & Toxicology

Loss of altruism in the social amoeba Dictyostelium discoideum is associated with the G protein-coupled receptor grlG

L. M. Walker, R. N. Sherpa, S. Ivaturi, D. A. Brock, J. R. Walker, J. E. Strassmann, D. C. Queller

The paper identifies genomic changes in Dictyostelium discoideum that correlate with the loss of cooperation and altruism, highlighting the role of the grlG gene.

bioRxiv · Oct 21, 2022Evolutionary Biology

Genomic and transcriptomic somatic alterations of hepatocellular carcinoma in non-cirrhotic livers

Z. L. Skidmore, J. Kunisaki, Y. Lin, K. C. Cotto, E. K. Barnell, J. Hundal, K. Krysiak, V. Magrini, L. Trani, J. R. Walker, R. Fulton, E. Brunt, C. A. Miller, R. K. Wilson, E. R. Mardis, , O. L. Griffith

This study identifies genomic and transcriptomic alterations in non-cirrhotic hepatocellular carcinoma, revealing recurrent mutations and structural variants that may contribute to tumorigenesis.

bioRxiv · Dec 14, 2021Cancer Biology

In vitro and in vivo analysis of microvesicle-mediated metastasis using a bright, red-shifted bioluminescent reporter protein of extracellular vesicles

A. A. Zarea, G. I. Perez, D. Broadbent, B. Dolgikh, M. P. Bernard, A. Withrow, A. McGill, V. Toomajian, L. K. Thampy, J. Harkema, J. R. Walker, T. A. Kirkland, M. H. Bachmann, J. Schmidt, M. Kanada

This study uses a bioluminescent reporter to track extracellular vesicles in vivo and shows their role in metastasis by upregulating LC3 in lung tissue.

bioRxiv · Jul 23, 2021Cancer Biology

Fatal neuroinvasion and SARS-CoV-2 tropism in K18-hACE2 mice is partially independent on hACE2 expression

M. Carossino, P. Montanaro, A. O'Connell, D. Kenney, H. Gertje, K. Grosz, M. Ericsson, B. R. Huber, S. Subramaniam, T. A. Kirkland, J. R. Walker, K. P. Francis, A. D. Klose, N. Paragas, S. Kurnick, , N. Crossland

This study investigates SARS-CoV-2 infection in K18-hACE2 mice, showing neuroinvasion and neuronal injury are key to lethality, with viral tropism not fully dependent on hACE2 expression.

bioRxiv · Jan 13, 2021 · PreprintPathology