ImmunologybioRxiv
Street RABV induces the cholinergic anti-inflammatory pathway in human monocyte-derived macrophages by binding to nAChr-a7, and upregulates the M2-c marker CD163
C. W. E. Embregts, L. Begeman, C. J. Voesenek…·C. H. Geurtsvankessel
This paper shows that street RABV binds to nAChr-a7 on human macrophages, inducing the cholinergic anti-inflammatory pathway and promoting an anti-inflammatory M2-c phenotype.
DOI 10.3389/fimmu.2021.622516