Breast cancer endocrine therapy exhausts adipocyte progenitors promoting weight gain and glucose intolerance
R. L. Scalzo, R. M. Foright, S. E. Hull, L. A. Knaub, S. Johnson-Murguia, F. Kinanee, J. Kaplan, B. Freije, G. Verzosa, J. A. Houck, G. Johnson, A. M. Y. Zhang, J. D. Johnson, P. S. MacLean, J. E. B. Reusch, , E. A. Wellberg
This study shows that breast cancer endocrine therapies deplete adipocyte progenitors and promote weight gain and glucose intolerance, especially in obese mice.
bioRxiv · Aug 21, 2020 · PreprintPhysiology