A long-acting GDF15 analog causes robust, sustained weight loss and reduction of food intake in an obese non-human primate model
S. Zheng, D. Polidori, Y. Wang, B. Geist, X. Lin-Schmidt, J. Furman, S. Nelson, A. Nawrocki, S. A. Hinke
This paper develops a long-acting GDF15 analog that reduces food intake and body weight in obese monkeys, with potential for clinical obesity treatment.
bioRxiv · Dec 5, 2022Pharmacology & Toxicology