A unified view of neighbour cell engagement during apoptotic cell extrusion.
K. Duszyc, G. Gomez, A. Lagendijk, M.-K. Yau, B. Gliddon, T. Hall, S. Verma, B. Hogan, S. Pitson, D. Fairlie, R. Parton, A. Yap
This study identifies RhoA activation via a Myosin VI-dependent mechanotransduction pathway as the mechanism by which apoptotic cells engage neighboring cells for extrusion, with S1P providing priming.
bioRxiv · Aug 6, 2020 · PreprintCell Biology