Gαq modulates the energy metabolism of osteoclasts
S. Chakraborty, B. Handrick, D. Yu, K. Bode, A. Hafner, J. Schenz, D. Schaack, F. Uhle, T. Tachibana, S. Kamitani, T. Vogl, K. Kubatzky
This study shows that Gαq enhances osteoclast energy metabolism by promoting glycolysis and mitochondrial respiration, contributing to increased bone resorption.
bioRxiv · Apr 6, 2022Immunology