Disruption of the Pseudomonas aeruginosa Tat system perturbs PQS-dependent quorum sensing and biofilm maturation through loss of the Rieske cytochrome bc1 sub-unit
E. Y.-C. Soh, F. Smith, M. Gimenez, L. Yang, R. Vejborg, M. Fletcher, N. Halliday, S. Bleves, S. Heeb, M. Camara, M. Givskov, K. Hardie, T. Tolker-Nielsen, B. Ize, P. Williams
This study identifies the Pseudomonas aeruginosa Tat pathway's role in PQS-dependent quorum sensing and biofilm maturation by showing that disruption of the Rieske cytochrome bc1 subunit impairs virulence factor production and eDNA release.
bioRxiv · Mar 1, 2021Microbiology