M. Fletcher

Chromosomal fusion drives sex chromosome evolution in treehoppers despite long-term X chromosome conservation

The paper examines X chromosome evolution in treehoppers, finding long-term conservation with one exception of an X-autosome fusion in a species.

An ultrasensitive microfluidic approach reveals correlations between the physico-chemical and biological activity of experimental peptide antibiotics

This study uses microfluidic platforms to show strong correlations between peptide antibiotics' physicochemical membrane activity and their cellular biological activity.

Measuring thousands of single vesicle leakage events reveals the mode of action of antimicrobial peptides

The paper uses high-resolution microscopy to study antimicrobial peptides' effects on vesicles, revealing their modes of action through detailed disruption measurements.

Disruption of the Pseudomonas aeruginosa Tat system perturbs PQS-dependent quorum sensing and biofilm maturation through loss of the Rieske cytochrome bc1 sub-unit

This study identifies the Pseudomonas aeruginosa Tat pathway's role in PQS-dependent quorum sensing and biofilm maturation by showing that disruption of the Rieske cytochrome bc1 subunit impairs virulence factor production and eDNA release.

Global transcriptional regulation of innate immunity in C. elegans

The paper identifies ATF-7 as a key transcriptional regulator of the innate immune response in C. elegans through genomic analysis of pathogen-induced gene regulation.