Opposing roles of blood-borne monocytes and tissue-resident macrophages in limbal stem cell damage after ocular injury
C. Zhou, F. Lei, M. Mittermaier, B. Ksander, R. Dana, C. H. Dohlman, D. G. Vavvas, J. Chodosh, E. I. Paschalis
This study shows that limbal stem cell damage after ocular injury is mediated by peripheral monocytes rather than direct chemical injury, with tissue-resident macrophages providing protection.
bioRxiv · Jul 25, 2021Immunology