Replication kinetic, cell tropism and associated immune responses in SARS-CoV-2 and H5N1 virus infected human iPSC derived neural models
L. Bauer, B. Lendemeijer, L. Leijten, C. W. E. Embregts, B. Rockx, S. A. Kushner, F. M. S. de Vrij, D. van Riel
This study compares SARS-CoV-2 and H5N1 virus replication, cell tropism, and immune responses in human iPSC-derived neural cultures, finding sparse SARS-CoV-2 infection with immune activation versus efficient H5N1 replication.
bioRxiv · Mar 15, 2021Microbiology