Pre-clinical Evaluation of Biomarkers for Early Detection of Nephrotoxicity Following Alpha-particle Radioligand Therapy
M. Li, C. Robles-Planells, D. Liu, S. A. Graves, G. Vasquez-Martinez, G. Mayoral-Andrade, D. Lee, P. Rastogi, B. M. Marks, E. A. Sagastume, R. M. Weiss, S. C. Linn-Peirano, F. L. Johnson, M. K. Schultz, D. Zepeda-Orozco
This study evaluates urinary NGAL as a non-invasive biomarker for early detection of tubular damage and long-term nephrotoxicity from alpha-particle radioligand therapy in mice.
bioRxiv · Sep 27, 2023Pharmacology & Toxicology