Visualizing the chaperone-mediated folding trajectory of the G protein β5 β-propeller
S. Wang, M. I. Sass, Y. Kwon, W. G. Ludlam, T. M. Smith, E. J. Carter, N. E. Gladden, M. Riggi, J. H. Iwasa, B. M. Willardson, P. S. Shen
This study visualizes the chaperone-mediated folding trajectory of Gβ5 using cryo-EM, showing how CCT stabilizes intermediates to fold the β-propeller domain.
bioRxiv · May 4, 2023Biochemistry