Imprinted anti-hemagglutinin and anti-neuraminidase antibody responses after childhood infections of A(H1N1) and A(H1N1)pdm09 influenza viruses
P. Daulagala, B. Mann, K. Leung, E. Lau, L. Yung, R. Lei, S. I. N. Nizami, J. T. Wu, S. S. Chiu, R. S. Daniels, N. C. Wu, D. E. Wentworth, J. S. M. Peiris, H.-L. Yen
The paper characterizes anti-HA and anti-NA antibody responses to A(H1N1) and A(H1N1)pdm09 influenza viruses in individuals born between 1950-2015, finding age-dependent imprinting and cross-reactivity to multiple antigenic variants.
bioRxiv · Feb 1, 2023Microbiology