A duplexed CRISPRi-based approach to predict synergistic antibiotic targets in Escherichia coli.
X. Xiong, H. Furseth, B. McCoy, L. Slavic, X. Yuan, S. Chen, A. D. Baughn, Y. Minato, W. R. Harcombe
The paper uses CRISPRi to predict synergistic antibiotic targets in E. coli by testing gene co-repression and identifying novel interactions.
bioRxiv · May 15, 2024 · PreprintMicrobiology