X. Yuan

This study evaluates a multivalent mRNA vaccine against SARS-CoV-2 variants in mice, showing broad protection against multiple strains.

This study identifies STN LFP features, including beta and gamma oscillations and the low-high power ratio, that correlate with sleep fragmentation in Parkinson's disease patients.

This study examines TLS in HCC treated with neoadjuvant immunotherapy, finding TLS correlate with better outcomes and show distinct morphological and functional features in tumor regression.

This study uses microfluidic impedance cytometry to analyze the cellular state changes in Hela cells treated with paclitaxel and vinblastine, showing distinct electrical parameter shifts during mitotic arrest and apoptosis.

Zotatifin targets EIF4A to suppress TNBC by inhibiting Sox4, inducing interferon response, and reprogramming the tumor immune microenvironment, synergizing with chemotherapy.

This paper introduces SINCS, a compression method for multidimensional biomedical images that improves efficiency and quality by leveraging semantic redundancy and saliency maps.

This study investigates the subcellular localization and function of duplicated FCaBP genes in L. passim, showing their role in flagellar structure and function through interactions with the BBSome complex.

This study investigates how carotenoid assembly affects quinone diffusion and the structure of the reaction center-light harvesting complex in Roseiflexus castenholzii.

The paper identifies the exoproteome of the honey bee trypanosomatid parasite Lotmaria passim and shows that an aspartyl protease is essential for efficient infection of the host.

This paper shows that a chitosan oligosaccharide analog disrupts fungal cell wall organization by targeting PHR transglucosidases, leading to antifungal activity and synergy with existing fungicides.

This study investigates the evolutionary history of the TMEM16 family in metazoans, identifying subfamily origins, gene duplications, and functional adaptations through genomic analysis.

This study identifies myeloid HIF1A as a cardio-protective factor during ischemia and reperfusion, mediated by netrin-1 induction in neutrophils.

This paper identifies and calibrates ultrabright localizations in SMLM to improve quantification accuracy for biomolecular organization.

This study uses multinuclear MRI to assess early efficacy of stem cell therapy in stroke by monitoring sodium homeostasis and lactate levels in treated animals.

This study characterizes the structure and function of DWV 3C protease, revealing a diverse catalytic triad among insect RNA viruses and potential inhibitors for controlling DWV infection.

This study constructs a single-cell transcriptome atlas of multiple myeloma patients stratified by R-ISS, identifies PC subsets and immunotargets, and links them to prognosis and EBV infection.

This study evaluates eVLP-based vaccine candidates against SARS-CoV-2 variants, showing that a trivalent vaccine induces broader immunity compared to single-variant vaccines.

The paper develops a cell-adaptable hydrogel with stem cells to improve spinal cord injury repair by reducing neuroinflammation and enhancing axonal growth in rats.

This paper develops a CRISPR/Cas13a system combined with super resolution imaging for direct, amplification-free viral RNA detection with improved sensitivity.

This study identifies multiple triggering factors for mutation repair in RNA viruses and shows that cell-to-cell movement enhances mutation repair, opposing the Muller ratchet effect.

This study shows that WWP1 deficiency protects against cardiac remodeling and function decline caused by simulated microgravity in mice.

This study shows HO-2 binds and buffers oxidized labile heme in HEK293 cells, regulating heme homeostasis by controlling bioavailability rather than degrading heme under non-stress conditions.

This paper introduces MLC-Seq, a method to sequence full-length tRNA isoforms and quantify RNA modifications, demonstrating its application on yeast and mouse tRNAs.

The paper identifies a novel IRES in WYMV RNA2 with variable eIF4E-binding sites and synergistic effects that enhance IRES activity.

This study investigates stochastic motion of biomolecules in SMLM and shows that restricting this motion improves localization precision.

This study characterizes the dynamic changes in B-cell receptor repertoires of COVID-19 patients using next-generation sequencing, revealing clonotype overlap, lineage expansion, and V gene usage patterns.

This study assesses the reporting quality of trend analyses in leading medicine and oncology journals from 2008-2018, finding moderate quality with room for improvement.

This paper analyzes B cell epitopes of SARS-CoV-2 spike protein variants to assess their impact on antigenicity and vaccine efficacy.

This study evaluates the virucidal activity and safety of Povidone-iodine in-situ gel formulations against SARS-CoV-2 in vitro and in vivo.