Author

B. McDonagh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Assay:proteomics· 2

Frequent Co-Authors

C. L. Mendias· 2 shared K. Goljanek-Whysall· 2 shared A. Arroquia-Soriano· 1 shared A. H. Qasawa· 1 shared A. N. Malik· 1 shared A. N. Piacentini· 1 shared A. Soriano-Arroquia· 1 shared C. A. Chinda· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersPhysiology

C. L. Mendias

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Author profile →

4 papers

Recent·Most cited

miR-24:Prdx6 interactions regulate oxidative stress and viability of myogenic progenitors during ageing

K. Goljanek-Whysall, A. Arroquia-Soriano, J. Gostage, D. Bardell, E. McCloskey, I. Bellantuono, P. D. Clegg, B. McDonagh

This study shows miR-24-3p and its target Prdx6 regulate oxidative stress and viability of myogenic progenitors during ageing, with miR-24 downregulation in old mice linked to increased ROS and satellite cell senescence.

bioRxiv · Jan 25, 2021 · PreprintCell Biology

Multiomics Analysis of the mdx/mTR Mouse Model of Duchenne Muscular Dystrophy

D. W. Van Pelt, Y. A. Kharaz, D. C. Sarver, L. R. Eckhardt, J. T. Dzierzawski, N. P. Disser, A. N. Piacentini, E. Comerford, B. McDonagh, C. L. Mendias

The paper uses multiomics analysis to study dystrophic muscles in mdx/mTR mice, finding transcriptome and proteome changes related to protein balance and metabolism, with limited agreement between transcriptome and proteome fold changes.

bioRxiv · Oct 25, 2019Physiology

miR-181a Regulates p62/SQSTM1, Parkin and Protein DJ-1 Promoting Mitochondrial Dynamics in Skeletal Muscle Ageing

K. Goljanek-Whysall, A. Soriano-Arroquia, R. McCormick, C. A. Chinda, B. McDonagh

This study shows miR-181a regulates mitochondrial dynamics in skeletal muscle ageing by controlling p62/SQSTM1, Parkin, and DJ-1, and restoring miR-181a improves mitochondrial quality and muscle function in aged mice.

bioRxiv · Oct 16, 2019Physiology

Reduced mitochondrial lipid oxidation leads to fat accumulation in myosteatosis

J. P. Gumucio, A. H. Qasawa, P. J. Ferrara, A. N. Malik, K. Funai, B. McDonagh, C. L. Mendias

This study identifies mitochondrial dysfunction and reduced fatty acid oxidation as causes of lipid accumulation in myosteatosis using a rat rotator cuff injury model.

bioRxiv · Nov 18, 2018Physiology