Author

E. Comerford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Pathology· 2 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Elsheikh· 2 shared B. Geraghty· 2 shared B. Poulet· 2 shared C. L. Mendias· 2 shared G. Bou-Gharios· 2 shared L. Ramos-Mucci· 2 shared R. Readioff· 2 shared Y. A. Kharaz· 2 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersPathology

A. Elsheikh

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Author profile →

6 papers

Recent·Most cited

Biomechanics of aging and osteoarthritic human knee ligaments

A. E. Peters, B. Geraghty, K. T. Bates, R. Akhtar, R. Readioff, E. Comerford

This study examines how aging and osteoarthritis affect the mechanical properties of four major human knee ligaments, finding significant declines in key parameters with age and OA severity.

bioRxiv · Nov 21, 2021 · PreprintBioengineering

The anterior cruciate ligament in murine post-traumatic osteoarthritis: markers and mechanics

L. Ramos-Mucci, A. Elsheikh, C. Keenan, A. Eliasy, K. D'Aout, G. Bou-Gharios, E. Comerford, B. Poulet

This study examines structural, cellular, and viscoelastic changes in the ACL of a murine PTOA model, finding ECM modifications and altered biomechanics.

bioRxiv · Nov 8, 2021Pathology

Viscoelastic characteristics of the canine cranial cruciate ligament complex at slow strain rates

R. Readioff, B. Geraghty, A. Elsheikh, E. Comerford

This study examines the viscoelastic properties of canine cranial cruciate ligaments under different strain rates and protocols, finding strain rate-dependent hysteresis and recovery.

bioRxiv · Sep 26, 2020Bioengineering

Scleraxis is required for the growth of adult tendons in response to mechanical loading

J. P. Gumucio, M. M. Schonk, Y. A. Kharaz, E. Comerford, C. L. Mendias

This study shows that scleraxis is necessary for adult tendon growth in response to mechanical loading by promoting pericyte commitment to tenocytes and extracellular matrix production.

bioRxiv · Mar 18, 2020Cell Biology

Multiomics Analysis of the mdx/mTR Mouse Model of Duchenne Muscular Dystrophy

D. W. Van Pelt, Y. A. Kharaz, D. C. Sarver, L. R. Eckhardt, J. T. Dzierzawski, N. P. Disser, A. N. Piacentini, E. Comerford, B. McDonagh, C. L. Mendias

The paper uses multiomics analysis to study dystrophic muscles in mdx/mTR mice, finding transcriptome and proteome changes related to protein balance and metabolism, with limited agreement between transcriptome and proteome fold changes.

bioRxiv · Oct 25, 2019Physiology

Meniscal and ligament modifications in spontaneous and post-traumatic mouse models of osteoarthritis

L. Ramos-Mucci, B. Javaheri, R. van 't Hof, G. Bou-Gharios, A. A. Pitsillides, E. Comerford, B. Poulet

This study examines meniscal and ligament changes in two mouse OA models, finding increased mineralisation and chondrogenesis associated with cartilage degeneration.

bioRxiv · Oct 24, 2019Pathology