A synthetic peptide mimic kills Candida albicans and synergistically prevents infection
S. Schaefer, R. Vij, J. L. Sprague, S. Austermeier, H. Dinh, P. R. Judzewitsch, E. Seemann, B. Qualmann, A. K. Cain, N. Corrigan, M. S. Gresnigt, C. Boyer, M. D. Lenardon, S. Brunke
This study identifies synthetic peptide mimics that kill Candida albicans and synergize with caspofungin to prevent infection, showing efficacy in vitro and in vivo without resistance development.
bioRxiv · Sep 25, 2023Microbiology