Author

R. Vij

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:proteomics· 5 Organism:fungi (other)· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:host-pathogen & immune response· 2 Assay:imaging· 2 Organism:mouse· 2

Frequent Co-Authors

A. Casadevall· 4 shared R. Prados-Rosales· 2 shared A. Bergman· 1 shared A. Hamacher-Brady· 1 shared A. K. Cain· 1 shared A. Locke· 1 shared A. Munoz-Barrutia· 1 shared A. Sneider· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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4 shared papersMicrobiology

A. Casadevall

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A synthetic peptide mimic kills Candida albicans and synergistically prevents infection

S. Schaefer, R. Vij, J. L. Sprague, S. Austermeier, H. Dinh, P. R. Judzewitsch, E. Seemann, B. Qualmann, A. K. Cain, N. Corrigan, M. S. Gresnigt, C. Boyer, M. D. Lenardon, S. Brunke

This study identifies synthetic peptide mimics that kill Candida albicans and synergize with caspofungin to prevent infection, showing efficacy in vitro and in vivo without resistance development.

bioRxiv · Sep 25, 2023Microbiology

Small extracellular vesicles promote stiffness-mediated metastasis

A. Sneider, Y. Liu, B. Starich, W. Du, C. Marar, N. Faqih, G. E. Ciotti, J. H. Kim, S. Krishnan, S. Ibrahim, M. Igboko, A. Locke, D. M. Lewis, H. Hong, M. Karl, , D. Wirtz

The paper shows that breast cancer cell-derived small extracellular vesicles (EVs) become more adhesive and metastatic when produced in stiff matrices, promoting cancer spread through enhanced chemotaxis and fibroblast reprogramming.

bioRxiv · Jul 1, 2023Cancer Biology

Bet-hedging antimicrobial strategies in macrophage phagosome acidification drive the dynamics of Cryptococcus neoformans intracellular escape mechanisms

Q. Dragotakes, E. Jacobs, L. S. Ramirez, O. I. Yoon, C. Perez-Stable, H. Eden, J. Pagnotta, R. Vij, A. Bergman, F. D'Alessio, A. Casadevall

This study identifies that stochastic phagosomal acidification and oxidative stress drive stochastic Dragotcytosis in Cryptococcus neoformans, enabling fungal escape from macrophages.

bioRxiv · Nov 29, 2021Microbiology

Variation in cell surface hydrophobicity among Cryptococcus neoformans strains influences interactions with amoeba

R. Vij, C. Crawford, A. Casadevall

This study shows that variation in cell surface hydrophobicity among Cryptococcus neoformans strains affects their interaction with amoeba and antibody binding.

bioRxiv · Dec 6, 2019Microbiology

The structural unit of melanin in the cell wall of the fungal pathogen Cryptococcus neoformans

E. Camacho, R. Vij, C. Chrissian, R. Prados-Rosales, D. Gil, R. N. O'Meally, R. J. Cordero, R. N. Cole, J. M. McCaffery, R. E. Stark, A. Casadevall

This study identifies the structural unit of melanin in the fungal pathogen Cryptococcus neoformans, revealing its organization into nanospheres and granules.

bioRxiv · May 21, 2019Microbiology

Listeria monocytogenes virulence factors are secreted in biologically active Extracellular Vesicles

C. Coelho, L. Brown, M. Maryam, M. C. Burnet, J. E. Kyle, H. M. Heyman, R. Vij, J. Ramirez, R. Prados-Rosales, G. Lauvau, E. S. Nakayasu, N. R. Brady, A. Hamacher-Brady, I. Coppens, A. Casadevall

This study shows Listeria monocytogenes secretes biologically active extracellular vesicles containing virulence factors like LLO and PI-PLC, which contribute to cytotoxicity in macrophages.

bioRxiv · Jan 20, 2018Microbiology