Pharmacology & ToxicologybioRxiv
Identification of Pirin as a Molecular Target of the CCG-1423/CCG-203971 Series of Anti-Fibrotic and Anti-Metastatic Compounds
E. M. Lisabeth, D. Kahl, I. Gopallawa…·R. R. Neubig
This study identifies pirin as the molecular target of the CCG-1423/CCG-203971 compounds, showing its role in modulating MRTF-dependent gene expression and fibrosis.
DOI 10.1021/acsptsci.8b00048