Design and Evaluation of Nanoscale Materials with Programmed Responsivity towards Epigenetic Enzymes
P. Ray, A. Sedigh, M. Confeld, L. Alhalhooly, K. Iduoku, G. Casanola-Martin, H. Pham-The, B. Rasulev, Y. Choi, Z. Yang, S. Mallik, M. Quadir
This paper designs and evaluates nanomaterials that disassemble in response to HDAC enzymes, revealing a mechanism based on deacetylation-induced amphiphilicity reduction.
bioRxiv · Mar 26, 2024Bioengineering