P. Ray

Design and Evaluation of Nanoscale Materials with Programmed Responsivity towards Epigenetic Enzymes

This paper designs and evaluates nanomaterials that disassemble in response to HDAC enzymes, revealing a mechanism based on deacetylation-induced amphiphilicity reduction.

Fish on the platter! Investigating the dietary habits of fishing cats (Prionailurus viverrinus) in the Godavari Delta, India

This study analyzes the diet of fishing cats in the Godavari Delta, finding fish as the primary prey, with seasonal variations in niche breadth and prey composition.

Treatment of pancreatic cancer with irreversible electroporation and intratumoral CD40 antibody stimulates systemic immune responses that inhibit liver metastasis in an orthotopic model.

Controllable self-replicating RNA vaccine delivered intradermally elicits predominantly cellular immunity

This paper develops a temperature-controlled self-replicating RNA vaccine that elicits cellular immunity and can be used as a pan-coronavirus booster.

Evaluation of ERIC-PCR and MALDI-TOF as typing tools for multidrug resistant Klebsiella pneumoniae clinical isolates from a tertiary care center in India

The paper evaluates ERIC-PCR and MALDI-TOF MS for typing multidrug-resistant Klebsiella pneumoniae isolates and finds ERIC-PCR more robust for clonal relatedness.

Plant-associated fungi support bacterial resilience following water limitation

This study shows that plant-associated fungi enhance bacterial resilience to water limitation by protecting their growth and diversity in hyphospheres.

Engineering Defensin α-helix to produce high-affinity SARS-CoV-2 Spike protein binding ligands.

This paper engineers defensin α-helices to create high-affinity SARS-CoV-2 Spike protein binding ligands for diagnostics and therapy.

Genomic rearrangements of mobile genetic elements associated with carbapenem resistance of Acinetobacter baumannii

This study characterizes genomic features of carbapenem-resistant Acinetobacter baumannii isolates from India, identifying resistance genes, mobile genetic elements, and clonal lineages.

Antibodies targeting conserved non-canonical antigens and endemic coronaviruses associate with favorable outcomes in severe COVID-19

The paper identifies antibody responses against non-canonical and endemic coronavirus antigens as predictors of favorable outcomes in severe COVID-19.

Comparative kinetic analysis of ascorbate (Vitamin-C) recycling dehydroascorbate reductases from plant and human.

This study compares the kinetic properties of plant and human DHAR enzymes, revealing differences in turnover rates and oxidation susceptibility that correlate with their cellular environments.

Dual avatars of E. coli grxB encoded Glutaredoxin 2 perform ascorbate recycling and ion channel activities

This study identifies two functional roles of EcGrx2: ascorbate recycling and ion channel activity, revealing its role in antioxidant defense and membrane integration in E. coli.

High-throughput, multiplex microfluidic test strip for the determination of antibiotic susceptibility in uropathogenic E. coli with smartphone detection

This paper evaluates a high-throughput microfluidic test strip for antibiotic susceptibility testing in uropathogenic E. coli, showing high agreement with standard methods.

Bifurcated monocyte states are predictive of mortality in severe COVID-19

The paper identifies bifurcated monocyte states in severe COVID-19 patients that predict mortality, with distinct cytokine and interferon gene modules associated with survival or death.

Effects of treatment with three antibiotics, vancomycin, neomycin, and AVNM on gut microbiome in C57BL/6 mice

This study examines how vancomycin, neomycin, and AVNM affect gut microbiota in C57BL/6 mice, showing differential changes in microbial composition, diversity, and host immune and metabolic responses.

Comparative metagenomic analysis following treatment with vancomycin in C57BL/6 and BALB/c mice to elucidate host immunity and behavior

This study compares metagenomic changes in Th1 and Th2 biased mice after vancomycin treatment, showing microbiota restoration and associated physiological and behavioral recovery.

An HIV-Tat inducible mouse model system of childhood HIV-associated nephropathy.

This paper develops an inducible mouse model of childhood HIV-associated nephropathy (HIVAN) and shows HIV-Tat contributes to the disease when combined with other HIV-1 genes and heparin-binding cytokines.

Comparative analysis of beneficial effects of Vancomycin treatment on Th1- and Th2-biased mice and role of gut microbiota

This study examines how vancomycin affects gut microbiota and immune profiles in Th1- and Th2-biased mice, finding that continued vancomycin treatment benefits Th1 mice more by reducing pathogens and increasing beneficial microbes.

An aptamer-based magnetic flow cytometer using matched filtering

This paper develops a magnetic flow cytometer using a GMR SV biosensor array and matched filtering to enable reliable point-of-care diagnostics for noncommunicable diseases.

Mutant EGFR is a preferred SMURF2 substrate of ubiquitination: role in enhanced receptor stability and TKI sensitivity

This paper identifies SMURF2-mediated ubiquitination of EGFR mutants as a mechanism enhancing receptor stability and TKI sensitivity.