Single-cell and spatial transcriptomics reveals the human liver immunological landscape and myeloid dysfunction in PSC.
T. S. Andrews, D. Nakib, C. Perciani, X. Z. Ma, L. Liu, E. Winter, D. Camat, S. Chung, J. Manuel, S. Mangroo, B. Hansen, B. Arpinder, C. Thoeni, B. Sayed, J. Feld, , S. A. MacParland
This paper uses single-cell and spatial transcriptomics to map the immune landscape of PSC livers, revealing myeloid dysfunction and cytokine-driven inflammation.
bioRxiv · Jul 28, 2023 · PreprintCell Biology