B. Hansen

Giardia Antagonizes Beneficial Functions of Indigenous and Therapeutic Intestinal Bacteria during Malnutrition

This study shows Giardia reduces the beneficial effects of Lactobacillus in malnourished mice, altering microbial balance and increasing intestinal damage.

Linear Mixed Model of Virus Disinfection by Chlorine to Harmonize Data Collected Across Broad Environmental Conditions

The paper develops a linear mixed model to estimate chlorine inactivation rate constants for viruses under varying environmental conditions and identifies discrepancies in current disinfection guidelines.

STING activation counters glioblastoma by vascular alteration and immune surveillance

This study shows that STING activation reduces glioblastoma progression and prolongs survival by altering tumor vasculature and enhancing immune surveillance.

Single-cell and spatial transcriptomics reveals the human liver immunological landscape and myeloid dysfunction in PSC.

This paper uses single-cell and spatial transcriptomics to map the immune landscape of PSC livers, revealing myeloid dysfunction and cytokine-driven inflammation.

Intra-islet glucagon signalling regulates pulsatile insulin secretion and glucose homeostasis

This study shows that loss of intra-islet glucagon receptor signaling impairs glucose tolerance and insulin pulsatility in mice, suggesting glucagonergic agents could restore insulin pulsatility in T2D.

Divergent acute versus prolonged pharmacological GLP-1R responses in adult beta cell-selective β-arrestin 2 knockout mice

This study examines GLP-1R responses in beta cell-specific β-arrestin 2 knockout mice, finding acute deficits and prolonged effects with certain agonists.

Structure of anchorless RML prion reveals motif variation between strains

Cryo-electron microscopy reveals a near-atomic structure of an infectious, brain-derived murine prion fibril and strain differences.

Structure of an infectious mammalian prion

This paper determines the structure of an infectious mammalian prion using cryo-electron microscopy, revealing its fibril architecture and molecular features involved in propagation.

Longitudinal, Multiparametric MRI Assessment of repetitive mild TBI in rats

This study uses longitudinal multiparametric MRI to detect microstructural and metabolic changes in rats with repetitive mild TBI, revealing alterations not visible with conventional imaging.