Author

B. Stevenson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 8

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:chromatin & epigenetic regulation· 4 Assay:DNA methylation· 3 Organism:human· 3 Organism:bacteria (other)· 2 Approach:genetic perturbation / CRISPR· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

T. C. Saylor· 5 shared C. A. Brissette· 4 shared N. Jusufovic· 4 shared A. C. Krusenstjerna· 3 shared W. R. Zueckert· 3 shared A. C. Krusensjerna· 2 shared A. Proulx· 1 shared A. S. Pramanik· 1 shared

Activity by Year

2018-2024 · peak 3/yr

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10 top collaborators · 20 mutual co-author links

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5 shared papersMicrobiology

T. C. Saylor

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8 papers

Recent·Most cited

DnaA modulates gene expression and morphology of the Lyme Disease spirochete

A. C. Krusensjerna, N. Jusufovic, T. C. Saylor, B. Stevenson

This study shows that DnaA modulates cell length, replication rate, and gene expression in Borrelia burgdorferi, affecting its morphology and virulence.

bioRxiv · Jun 8, 2024 · PreprintMicrobiology

Erp and Rev adhesins of the Lyme disease spirochete's ubiquitous cp32 prophages assist the bacterium during vertebrate infection

B. Stevenson, C. A. Brissette

The paper identifies Erp and Rev adhesins encoded by cp32 prophages in Lyme disease spirochetes, showing they enhance host interaction and infection.

Infection and Immunity · Mar 15, 2023Peer-reviewedMicrobiology

Quantitative analyses of interactions between SpoVG and RNA/DNA

T. C. Saylor, C. R. Savage, A. C. Krusensjerna, N. Jusufovic, W. R. Zueckert, C. A. Brissette, M. A. MOTALEB, P. J. Schlax, B. Stevenson

The paper quantifies SpoVG's binding affinities to various RNAs and DNAs, identifies high-affinity sites, and shows sequence/structure independence in complex formation.

bioRxiv · Feb 6, 2023Microbiology

Borrelia burgdorferi PlzA is a cyclic-di-GMP dependent DNA- and RNA-binding protein

N. Jusufovic, A. C. Krusenstjerna, C. Savage, T. C. Saylor, C. A. Brissette, W. R. Zueckert, P. Schlax, M. A. R. MOTALEB, B. Stevenson

This study identifies PlzA as a cyclic-di-GMP-dependent DNA and RNA-binding protein in Borrelia burgdorferi, showing that nucleic acid binding requires c-di-GMP and involves specific domain interactions.

bioRxiv · Jan 30, 2023Microbiology

Inducible CRISPRi-based operon silencing and selective in trans gene complementation in Borrelia burgdorferi

B. T. Murphy, J. J. Wiepen, H. He, A. S. Pramanik, J. M. Peters, B. Stevenson, W. R. Zueckert

This paper develops an inducible CRISPRi system for gene repression in Borrelia burgdorferi and demonstrates in trans complementation to study gene function.

bioRxiv · Dec 5, 2022Microbiology

Gac is a transcriptional repressor of the Lyme disease spirochete's OspC virulence-associated surface protein

T. N. Castro-Padovani, T. C. Saylor, O. T. Husted, A. C. Krusenstjerna, N. Jusufovic, B. Stevenson

This paper identifies Gac as a transcriptional repressor of the OspC virulence protein in Lyme disease spirochetes, showing its role in regulating OspC expression during infection.

bioRxiv · Nov 9, 2022 · PreprintMicrobiology

Borrelia burgdorferi DnaA and the nucleoid-associated protein EbfC coordinate expression of the dnaX-ebfC operon

A. C. Krusenstjerna, T. C. Saylor, W. K. Arnold, J. S. Tucker, B. Stevenson

This study shows that DnaA and EbfC interact at the dnaX-ebfC 5 UTR to regulate operon expression, linking replication rate to virulence factor expression in Borrelia burgdorferi.

bioRxiv · Oct 17, 2022 · PreprintMicrobiology

DNA Methylation by Restriction Modification Systems Affects the Global Transcriptome Profile in Borrelia burgdorferi

T. Casselli, Y. Tourand, A. Scheidegger, W. Arnold, A. Proulx, B. Stevenson, C. A. Brissette

This study identifies DNA methylation patterns and their impact on gene expression in Borrelia burgdorferi using restriction modification systems.

bioRxiv · Jul 24, 2018Microbiology