Lipoproteome screening of the Lyme disease agent identifies novel inhibitors of antibody-mediated complement killing
M. J. Pereira, B. Wager, R. J. Garrigues, E. Gerlach, J. D. Quinn, A. Dowdell, M. S. Osburne, W. R. Zuckert, P. Kraiczy, B. L. Garcia, J. M. Leong
This study identifies two B. burgdorferi lipoproteins that inhibit complement C1 proteases, providing a novel mechanism for antibody-mediated complement evasion.
bioRxiv · Sep 23, 2021Microbiology