Author

B. Weigelin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Assay:imaging· 2 Organism:mouse· 2 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Approach:statistical model· 1

Frequent Co-Authors

P. Friedl· 2 shared A. Messent· 1 shared A. T. den Boer· 1 shared B. Lelli· 1 shared C. G. Figdor· 1 shared D. J. Lefeber· 1 shared E. Wagena· 1 shared H. Dolstra· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

P. Friedl

Mutual co-authors in cluster

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3 papers

Recent·Most cited

CD137-stimulated cytotoxic T lymphocytes exert superior tumour control due to an enhanced antimitotic effect on tumour cells

R. Beck, B. Weigelin, J. Beltman

This study uses mathematical models of two-photon imaging data to show that CD137 stimulation enhances tumour control by increasing CTL antiproliferative effects and prolonging their tumour residency.

bioRxiv · Dec 15, 2020Cancer Biology

Glycocalyx-mediated Cell Adhesion and Migration

S. Schmidt, B. Weigelin, J. te Riet, V. te Boekhorst, M. te Lindert, M. Wijers-Rouw, B. Lelli, L. Rognoni, M. Krause-Vortmeyer, A. Messent, L. Bracci, K. E. Gottschalk, S. Kissler, M. Humphries, D. J. Lefeber, , P. Friedl

This study shows the glycocalyx enables cell adhesion and amoeboid migration through nanoscale interactions and mechano-coupling, independent of integrin function.

bioRxiv · Jun 12, 2020 · PreprintCell Biology

Cancer cell elimination by cytotoxic T cell cooperation and additive damage

B. Weigelin, A. T. den Boer, E. Wagena, K. Broen, H. Dolstra, R. J. de Boer, C. G. Figdor, J. Textor, P. Friedl

The paper shows that cytotoxic T cells eliminate cancer cells through multiple sublethal interactions rather than a single lethal hit, highlighting additive cytotoxicity in vivo.

bioRxiv · Apr 22, 2020Immunology