Cell BiologyScience Translational MedicinePeer-reviewed
A transcriptional atlas of the pubertal human growth plate reveals direct stimulation of cartilage stem cells by growth hormone.
Nelson Tsz Long Chu, Ostap A. Dregval, Farasat Zaman…·Andrei S. Chagin
This study reveals GH directly stimulates human growth plate stem cell proliferation via TGF{beta} and ERK pathways, offering insights into growth mechanisms and treatment optimization.
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