Cell BiologybioRxivPreprint
MT5-MMP C-terminal mutations reduce C99 and β accumulation: A foundation for peptide-based Alzheimer's interventions
Pedro Belio Mairal, Athina Kamitsou, Delphine Stephan…·Santiago Rivera
This study shows that specific mutations in the C-terminal domains of MT5-MMP reduce C99 and Aβ levels, suggesting a potential therapeutic strategy for Alzheimer's disease.
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