Author

Barbara Leon

Novartis (Switzerland)

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1

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Daniel K. NomuraiD· 1 shared Emily Ho· 1 shared Grace ZhouiD· 1 shared Halime Yilmaz· 1 shared Hannah R. Grupe· 1 shared James A. OlzmanniD· 1 shared Lauren M. OrriD· 1 shared Melissa Lim· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperBiochemistry

Daniel K. NomuraORCID

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1 paper

Recent·Most cited

BiochemistryACS Central SciencePeer-reviewedJun 26, 2025

DCAF16-Based Covalent Degradative Handles for the Modular Design of Degraders

Lauren M. Orr, Sydney J. Tomlinson, Hannah R. Grupe…·Daniel K. Nomura

This paper identifies a covalent degradative handle that can be transplanted onto various protein-targeting ligands to induce degradation of their targets, enabling modular degrader design.

20 citationstop 2%

experimental assaydrug response / drug discovery

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