Author

Barbara Zieger

University of Freiburg

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Molecular Biology· 1

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Approach:experimental assay· 1 Organism:human· 1

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Christian GorzelannyiD· 1 shared Christoph SchelliD· 1 shared Eva L. DeckeriD· 1 shared Hong WangiD· 1 shared Jens PanseiD· 1 shared Jessika Kleindienst· 1 shared Karsten HäffneriD· 1 shared Manuel RoggiD· 1 shared

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1 shared paperMolecular Biology

Christian GorzelannyORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintJul 31, 2024

Thrombospondin-1 inhibits alternative complement pathway activation in vasculitis synergistically to factor H

Swagata Konwar, Sophie Schroda, Jessika Kleindienst…·Karsten Häffner

This study identifies TSP-1 as a FH-independent inhibitor of the alternative complement pathway, showing its role in vasculitis by modulating complement activation and NETosis.

DOI 10.1101/2024.07.31.606000

humanexperimental assay

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