GeneticsbioRxivPreprint
Two variance component model improves genetic prediction in family data sets
George Tucker, Po-Ru Loh, Iona M MacLeod…·Alkes L Price
This paper introduces a two variance component model that improves genetic prediction in family data by jointly modeling IBS sharing and pedigree structure, achieving higher prediction accuracy and correcting inflated test statistics.
DOI 10.1101/016618