BiochemistrybioRxivPreprint
Compensatory tRNA Modification by DUS3L Confers Resistance to METTL1 Loss in Oesophageal Cancer
Helena Santos-Rosa, Jonathan L. Price, Georgia Tsagkogeorga…·Eric Alexander Miska
The paper identifies a compensatory tRNA modification pathway mediated by DUS3L that allows oesophageal cancer cells to resist METTL1 loss, suggesting DUS3L as a biomarker and therapeutic target.
DOI 10.1101/2025.10.13.682082