BiophysicsbioRxiv
Mn2+-Induced Structural Flexibility Enhances the Entire Catalytic Cycle and the Cleavage of Mismatches in Prokaryotic Argonaute Proteins
Lirong Zheng, Bingxin Zhou, Yu Yang…·Liang Hong
This study shows that Mn2+ enhances pAgo protein flexibility, improving catalytic efficiency and mismatch cleavage through structural changes.
DOI 10.1039/d3sc06221j