PathologyCirculationPeer-reviewed
Exploring Integrin α5β1 as a Potential Therapeutic Target for Pulmonary Arterial Hypertension: Insights from Comprehensive Multicenter Preclinical Studies
Sarah-Eve S Lemay, Mónica S. Montesinos, Yann Grobs…·Sébastien Bonnet
The study identifies integrin α5β1 as a key driver of pulmonary vascular remodeling in PAH and shows its inhibition improves hemodynamics and RV function in preclinical models.
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