Author

Blythe Durbin-Johnson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2

Frequent Co-Authors

David M RockeiD· 2 shared J. Jared Gossett· 2 shared Luyao Ruan· 2 shared Sharon Aviran· 2 shared Yilun Zhang· 1 shared

Activity by Year

2015-2015 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersBioinformatics

David M RockeORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJun 11, 2015

Excess False Positive Rates in Methods for Differential Gene Expression Analysis using RNA-Seq Data

David M Rocke, Luyao Ruan, Yilun Zhang…·Sharon Aviran

The paper evaluates differential gene expression methods using RNA-Seq data and finds that methods relying on negative binomial models show high false positive rates, while variance-based methods do not.

DOI 10.1101/020784

bulk RNA-seqstatistical model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintApr 30, 2015

Controlling False Positive Rates in Methods for Differential Gene Expression Analysis using RNA-Seq Data

David M Rocke, Luyao Ruan, J. Jared Gossett…·Sharon Aviran

The paper evaluates differential gene expression methods using RNA-Seq data, finding that many produce false positives and recommends limma-voom and simple methods for better performance.

DOI 10.1101/018739

bulk RNA-seqstatistical model

𝕏 PostBluesky