Longitudinal Fragility phenotyping predicts lifespan and age-associated morbidity in C57BL/6 and Diversity Outbred mice
Alison Luciano, Laura L. Robinson, Gaven Garland, Bonnie L. Lyons, Ron Korstanje, Andrea Di Francesco, Gary A. Churchill
This study uses frailty phenotyping to predict lifespan and age-associated morbidity in mice, finding it has significant predictive power but not sufficient reliability for advanced lifespan prediction.
bioRxiv · Feb 6, 2024 · PreprintBioinformatics