Author

Gaven Garland

Jackson Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:genome assembly· 1 Research Focus:GWAS / association mapping· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Laura L. Robinson· 4 shared Gary A. ChurchilliD· 3 shared Ron KorstanjeiD· 3 shared Adam FreundiD· 2 shared Alison Luciano· 2 shared Andrea Di FrancescoiD· 2 shared Andrew G. DeighaniD· 2 shared Anil RajiD· 2 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenetics

Laura L. Robinson

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

APOE is a presynaptic protein that accumulates with age and modulates neurotransmitter release

Sarayut Phasuk, Kyla B. Tooley, Julianna L. Sun, Vishwajeeth Pagala, Gustavo Palacios, Sean Deats, Gaven Garland, Laura L. Robinson, Xusheng Wang, Bonn Belingon, Jenn Cook, Haiyan Tan, Ankhbayar Lkhagva, Zuo-Fei Yuan, Long Wu, , Jason Vevea

This study identifies APOE as a presynaptic protein enriched in aged female mice, showing it modulates neurotransmitter release and affects synaptic function.

bioRxiv · Apr 21, 2026 · PreprintNeuroscience

Regulators of health and lifespan extension in genetically diverse mice on dietary restriction

Andrea Di Francesco, Andrew G. Deighan, Lev Litichevskiy, Zhenghao Chen, Alison Luciano, Laura L. Robinson, Gaven Garland, Hannah Donato, Matthew J. Vincent, Will Schott, Kevin M. Wright, Anil Raj, G.V. Prateek, Martin N. Mullis, Warren G. Hill, , Gary A. Churchill

In 937 genetically diverse female mice, caloric restriction and intermittent fasting extended lifespan, yet bodyweight resilience, immune and red-cell traits, not metabolic improvements, predicted longevity.

Nature · Oct 9, 2024Peer-reviewedGenetics✦ In-depth digest

Longitudinal Fragility phenotyping predicts lifespan and age-associated morbidity in C57BL/6 and Diversity Outbred mice

Alison Luciano, Laura L. Robinson, Gaven Garland, Bonnie L. Lyons, Ron Korstanje, Andrea Di Francesco, Gary A. Churchill

This study uses frailty phenotyping to predict lifespan and age-associated morbidity in mice, finding it has significant predictive power but not sufficient reliability for advanced lifespan prediction.

bioRxiv · Feb 6, 2024 · PreprintBioinformatics

Intermittent fasting and caloric restriction interact with genetics to shape physiological health in mice

Guozhu Zhang, Andrew G. Deighan, Anil Raj, Laura L. Robinson, Hannah Donato, Gaven Garland, Mackenzie Leland, Baby Martin-McNulty, Ganesh A. Kolumam, Johannes Riegler, Adam Freund, Kevin M. Wright, Gary A. Churchill

This study examines how caloric restriction and intermittent fasting interact with genetics to influence physiological health in mice, finding diet-specific effects and significant genetic contributions to multiple traits.

Genetics · Sep 25, 2021Peer-reviewedGenetics