Cancer BiologyBMC MedicinePeer-reviewed
Protein Translation Dysregulation and Immune Cell Evasion Define Metastatic Clones in HPV-related Cancer of the Oropharynx
Venessa T. Chin, Walter Muskovic, Rachael A. McCloy…·Joseph E. Powell
This study identifies mechanisms of immune evasion and metastasis in HPV-related oropharyngeal cancer using single-cell and spatial genomic data, showing dysregulated protein translation and immune pathway suppression in metastatic clones.