Systems BiologyIEEE AccessPeer-reviewed
Drug Target Identification in Triple Negative Breast Cancer Stem Cell Pathways: a computational study of gene regulatory pathways using Boolean networks
Aditya Lahiri, Haswanth Vundavilli, Madhurima Mondal…·Aniruddha A. Datta
This study uses Boolean networks to identify optimal drug targets in TNBC stem cell pathways, finding that inhibiting STAT3, GLI, and NF-κB can prevent relapse and that drug combinations are more effective.
10 citations