Author

Brissa Castillo

Texas A&M University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2

Frequent Co-Authors

Fiona Gugala· 2 shared Wanhe LiiD· 2 shared Feda Hammood· 1 shared Josh DubnauiD· 1 shared Kyle Huyghue· 1 shared Swetha Murthygowda· 1 shared Yangyuan LiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 15 mutual co-author links

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2 shared papersNeuroscience

Fiona Gugala

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2 papers

Recent·Most cited

Environmental modulation of social isolation-induced sleep loss in Drosophila

Brissa Castillo, Fiona Gugala, Yangyuan Li, Feda Hammood, Wanhe Li

This study examines how environmental factors during and after social isolation affect sleep loss in Drosophila, finding that sleep loss persists but is influenced by environmental context.

bioRxiv · Oct 2, 2026 · PreprintNeuroscience

Early life social isolation primes flies for more rapid TDP-43 dependent neurodegeneration later in life.

Swetha Murthygowda, Kyle Huyghue, Brissa Castillo, Fiona Gugala, Wanhe Li, Josh Dubnau

This study shows that early-life social isolation in flies accelerates TDP-43-related neurodegeneration later in life by enhancing mdg4 activation and pathologic propagation.

bioRxiv · Oct 1, 2026 · PreprintNeuroscience