ImmunologybioRxivPreprint
An ancient evolutionary origin for IL-1 cytokines as mediators of immunity
Francisco Fontenla-Iglesias, Tse-Mao Lin, Amelia G. Williams…·Sebastian D. Fugmann
This study identifies an ancient evolutionary origin of IL-1 cytokines in invertebrates, showing they share key features with mammalian IL-1 proteins and suggest a foundational role in animal immunity.
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