Author

C. A. Cotrell

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Biology Disciplines

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Biochemistry· 1

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. B. Ward· 1 shared B. S. Graham· 1 shared D. Wrapp· 1 shared H. L. Turner· 1 shared J. Pallesen· 1 shared J. S. McLellan· 1 shared K. S. Corbett· 1 shared N. Wang· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

A. B. Ward

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1 paper

Recent·Most cited

Receptor binding and proteolysis do not induce large conformational changes in the SARS-CoV spike

R. N. Kirchdoerfer, N. Wang, J. Pallesen, D. Wrapp, H. L. Turner, C. A. Cotrell, K. S. Corbett, B. S. Graham, J. S. McLellan, A. B. Ward

This study uses cryo-EM to show that ACE2 binding and trypsin cleavage of SARS-CoV spike protein do not cause major conformational changes or expose the S2 cleavage site.

bioRxiv · Mar 31, 2018Biochemistry