Author

C. A. McElroy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Bender· 1 shared A. Revnew· 1 shared D. Kumar Yadav· 1 shared E. C. Ihms· 1 shared M. Foster· 1 shared M. Holmquist· 1 shared P. Gollnick· 1 shared P. Shriwas· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Bender

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2 papers

Recent·Most cited

Development and characterization of pFluor50, a fluorogenic-based kinetic assay system for high-throughput inhibition screening and characterization of time-dependent inhibition and inhibition type for six human CYPs

P. Shriwas, A. Revnew, S. Roo, A. Bender, T. R. Lane, S. Ekins, C. A. McElroy

The paper develops pFluor50, a fluorogenic kinetic assay system for high-throughput inhibition screening of six human CYPs, determining KM, Vmax, and inhibition types.

bioRxiv · Aug 15, 2023Pharmacology & Toxicology

Solution structure, dynamics and tetrahedral assembly of Anti-TRAP, a homo-trimeric triskelion-shaped regulator of tryptophan biosynthesis in Bacillus subtilis

C. A. McElroy, E. C. Ihms, D. Kumar Yadav, M. Holmquist, V. Wadhwa, V. Wysocki, P. Gollnick, M. Foster

This study determines the solution structure and dynamics of Anti-TRAP, revealing its trimeric and dodecameric forms and their roles in TRAP inhibition.

bioRxiv · Jun 29, 2023 · PreprintBiochemistry